MOTS-c (MOTS-C)

buy in Ukraine

Metabolism · Energy · Anti-aging · Mounjaro Booster

Synonyms:MOTS-CMOTS-c peptideMOTS-c supplementMOTS-c mitochondrial peptideMOTS-c Pen Peptidemitochondrial peptide
4.8·71 reviews
4 250
In stock

Ships today · before 19:00

Delivery Sat, Jun 27 · Nova Poshta

MOTS-c (Motc-C, motc peptide, motc, moc preparation) — a mitochondrial peptide with 16 amino acids, discovered in 2015 at University of Southern California. Activates AMPK pathway, increases insulin sensitivity, accelerates fat metabolism, improves energy and endurance. Format: Pen Peptide pen, 10 mg (200 units × 50 mcg), manufacturer claims ≥98% purity, GMP + MSSPT formula. Protocol: 2.5 mg (50 pen units) subcutaneously once every 4–5 days — 20-day course. Cold chain 2–8°C. Effective booster for Mounjaro/Ozempic. Price ₴4,250. DOZA support 24/7.

Course20 days1 pen
Dosage2.5 mg (50 pen units) subcutaneously, once every 4–5 days
Price4,250
Administration💉 Pen Peptide injection pen
ResearchPubMed ↗
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One pen contains 10 mg (200 units × 50 mcg) — 4 course doses. For extended 40-day course, 2 pens needed. Break between courses 2–4 weeks. Can repeat 3–4 times per year.

Free specialist consultation

Benefits

  • Burns fat more efficiently through AMPK pathway
  • Improves mitochondrial metabolism
  • Increases insulin sensitivity and glucose tolerance
  • Protects muscles from catabolism, maintains muscle function
  • Increases physical endurance and energy
  • Improves cognitive functions and mental clarity
  • Improves sleep quality and recovery
  • Reduces chronic inflammation
  • Supports cardiovascular system
  • Slows aging processes and supports longevity

Who it's for

  • ✔️Those wanting to accelerate fat burning with Mounjaro weight loss program
  • ✔️With insulin resistance, prediabetes, or metabolic syndrome
  • ✔️Athletes for endurance improvement and muscle protection
  • ✔️With slow metabolism and weight loss difficulties
  • ✔️Those seeking to preserve energy and muscle mass during weight loss
  • ✔️With poor sleep quality and recovery problems
  • ✔️For cognitive function support and mental clarity
  • ✔️For anti-aging protocol — slowing aging and longevity

How to take

Dose: 2.5 mg (50 pen units) subcutaneously, once every 4–5 days (Pen Peptide manufacturer protocol).

Pen contains 10 mg = 200 units × 50 mcg. One pen — 4 doses (~20 days).

Course duration: 20 days (1 pen) or extended 40 days (2 pens).

Break between courses: 2–4 weeks. Can repeat 3–4 times per year.

Pen units table (1 unit = 50 mcg):

— 5 units = 250 mcg

— 10 units = 500 mcg

— 20 units = 1 mg

— 50 units = 2.5 mg (standard dose)

— 60 units = 3 mg

— 200 units = 10 mg (entire pen)

Injection technique:

— Inject subcutaneously in abdomen area or front thigh surface.

— After injection, wait 10 seconds before needle removal.

— Rotate injection sites (alternate sides).

— Recommended to inject in morning, before physical activity or meals.

Compatible peptides (Pen Peptide manufacturer recommends):

— Ipamorelin — GH stimulation, anti-aging and regeneration;

— CJC-1295 NO DAC — enhanced GH release from pituitary;

— PEG-MGF — muscle recovery and growth after exercise;

— NAD+ — enhanced mitochondrial energetics (DOZA combination).

Before starting — DOZA specialist consultation.

Full description

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) — a mitochondrial peptide with 16 amino acids, characterized in 2015 by Pinchas Cohen's laboratory at University of Southern California (first publication: Lee et al., Cell Metabolism, PubMed 25738459). Unlike most hormones, MOTS-c is encoded not by nuclear but by mitochondrial DNA — making it a unique signaling molecule for communication between mitochondria, cells, and organs.

Mechanism: activates AMPK pathway (the same "metabolic switch" as metformin), blocks fat accumulation and accelerates glucose metabolism. MOTS-c levels in the body decline with age — partially explaining the metabolic slowdown after 40.

Pen Peptide produces MOTS-c in pen injectors with pre-dissolved stabilized solution. Purity ≥98%, production in certified GMP laboratories, MSSPT molecular stabilization technology (buffers, antioxidants, stabilizing agents) — the formula preserves bioactivity even during brief temperature deviations during transportation.

Ideal booster for Mounjaro to accelerate fat burning without muscle mass loss.

Mechanism of action

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) — a mitochondrial signaling peptide with 16 amino acids. Main mechanism — activation of AMPK (AMP-activated protein kinase), the cellular "energy sensor" that regulates the balance between anabolism and catabolism.

After subcutaneous injection, MOTS-c enters the bloodstream and binds to receptors on muscle, liver, and adipose tissue cells. AMPK activation triggers a cascade of reactions: accelerates fatty acid oxidation (lipolysis), increases glucose uptake by muscles without insulin requirement, blocks new fat accumulation through acetyl-CoA carboxylase inhibition.

Simultaneously, MOTS-c improves mitochondrial function — increases mitochondrial quantity and efficiency (mitochondrial biogenesis), enhances ATP production (cellular energy). This explains the energy surge and endurance improvement in the first week of the course.

Additionally, MOTS-c increases tissue insulin sensitivity — critical for people with insulin resistance or metabolic syndrome. In Lee et al. study (Cell Metabolism 2015, PubMed 25738459), MOTS-c improved glucose tolerance in obesity models.

Endogenous MOTS-c levels decline with age — partially explaining metabolic slowdown after 40 years. Exogenous administration restores mitochondrial signaling and metabolic homeostasis.

Side effects & contraindications

MOTS-c in clinical studies and research practice has shown a good safety profile.

Rare side effects (according to Pen Peptide manufacturer):

— Mild nausea or stomach discomfort

— Headache

— Discomfort or redness at injection site

— Slight fatigue at course beginning (resolves in 2–3 days)

Contraindications: pregnancy, lactation, autoimmune diseases in active phase.

The preparation is intended for research purposes. Before use — specialist consultation.

Scientific research

📄
Read on PubMedPeer-reviewed study

Key MOTS-c publications (according to Pen Peptide manufacturer materials): 1. Lee et al., Cell Metabolism (2015) — discovered MOTS-c regulatory role in insulin sensitivity and metabolic homeostasis. PubMed 25738459. 2. Nature Communications (2018–2020) — human studies: participants receiving MOTS-c for 5 days showed improved cognitive performance and sleep quality versus placebo. 3. Cell Metabolism (athletes) — MOTS-c increased muscle function and physical endurance compared to control group. 4. Cell Metabolism (diabetic mice) — MOTS-c improved glucose regulation and promoted weight loss, indicating potential in type 2 diabetes management. Additionally: MOTS-c reduces oxidative stress markers and myostatin signals (muscle atrophy), critical for preserving muscle mass during GLP-1 weight loss.

Scientific evidence

Mitochondrial peptide (16 a.a.); insulin sensitivity enhancement, energy metabolism regulation.

MOTS-c is a research-stage mitochondrial-derived peptide; not approved by FDA, EMA or MOH of Ukraine. Used in academic research context only.

View full scientific evidence database →

Frequently Asked Questions about MOTS-c

DS

You can buy MOTS-c on DOZA website. Delivery across Ukraine via Nova Poshta in 1–2 days, cold chain 2–8°C. Price — ₴4,250.

DOZA Specialist

Client reviews

★★★★★Olena V.November 2025

MOTS-c — felt the effect after the first week. Fast delivery, everything in thermo-packaging. DOZA — thank you for the support!

★★★★★Andrii S.December 2025

Ordering MOTS-c for the second course already. Original quality, fair price. DOZA consultant answered all my questions.

All DOZA client results →

Before/after photos · numbers · timelines · reviews

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Buy MOTS-c in Ukraine — DOZA

MOTS-c is available in Ukraine through DOZA online service. Metabolism · Energy · Anti-aging · Mounjaro Booster. We ensure original quality, safe storage and delivery across Ukraine via Nova Poshta. Every order includes a free specialist consultation.

Price of MOTS-c — 4 250 ₴. For detailed information about dosage, course and suitability, please consult a DOZA specialist.

Buy MOTS-c with 1–2 day delivery across Ukraine. Cold chain 2–8°C. We respond 24/7.

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Information verified

Anastasia Shapoval

Metabolic Programs and Weight Control Specialist

Olena Kovalchuk

Medical Reviewer, Endocrinologist

Updated