How long do side effects last?

According to direct client reports — 1–4 days after the injection, mostly mild nausea in the first days. Across 11 months of conversations there is not a single case lasting over a week. 58% of clients explicitly reported feeling well.

Where does this data come from?

From client conversations with DOZA support between August 2025 and July 2026: 1,272 dialogues, of which 163 clients reported a numeric result. Data is anonymized; methodology and limitations are fully described in the report.

Why does the report include only some clients?

Only results with exact numbers were included — 163 of 908 clients (18%). Many clients replied "all good, the weight is coming off" without numbers or sent photos or voice messages — such replies were not counted, so the real number of results is higher than recorded.

Will the weight come back after the program ends?

The risk of regaining weight exists with abrupt discontinuation and unchanged habits. That is why DOZA support includes a gradual program exit, nutrition adjustments and maintenance recommendations. Some clients in this report have maintained their weight for over a year.

Key takeaway

Over 11 months (August 2025 — July 2026), 163 DOZA clients reported numeric weight-loss results: −1,026 kg in total, a median of −4.0 kg per client, and one in four losing over 10 kg. First-month median: −4.8 kg. Side effects, when present, lasted 1–4 days. Data was collected from support conversations, anonymized, with full methodology and limitations.

Retrospective analysisGeneraln = 163

DOZA Internal Outcomes Report · v1.0 · Published July 15, 2026 · updated quarterly

DOZA Client Outcomes Report 2025–2026

Study at a glance

Observation period: August 2025 — July 2026
Clients in report: n = 163
Data cut-off: 15.07.2026, 12:00 EEST
Report version: v1.0
Next update: October 2026

163

Clients with results

11 months · self-reported numbers

−1 026 kg

Total weight lost

August 2025 — July 2026

−4,0 kg

Median result

as of the latest report · mean −6.3 kg

−4,8 kg

First month

median, n=38 · reported at weeks 3–6

25%

Lost 10+ kg

one in four clients

1–4 days

Side effect duration

n=16 · among those who specified duration · no case lasting over a week

From base to every metric

Different report blocks rely on different denominators. Here is how the sample narrows from all clients to those who reported specific data.

1272

Dialogues in the support archive

full 11-month archive

908

Clients with a confirmed order

report base — 100%

163· 18% of base

Reported a numeric weight result

distribution, tempo, median

35· 3,9% of base

Sent body measurements (cm)

body volumes block

16· 1,8% of base

Specified side-effect duration

the “1–4 days” figure

Each block of the report relies on its own denominator. For example, “1–4 days” is n=16, not all 163 clients; the % of body weight is n=33. So the headline figures and the narrower metrics should not be conflated.

How much weight do DOZA clients lose?

Result distribution: weight loss range (kg) and number of clients in each range. For many clients the result is interim — their program continues.

0,5–2 кг

10%

2–4 кг

29%

4–6 кг

18%

6–8 кг

10%

8–10 кг

10–15 кг

16%

15–26 кг

25%

lost 10 kg or more

41 of 163 clients who reported a result

Body measurements reduction

35 clients · 64 measurements

−3,5 cm

Median per measured zone

−10 cm

Best result (belly)

Clients who sent tape measurements: waist, hips, chest, belly. A typical monthly report: waist −4…−6 cm, hips −2…−7 cm. Several clients noted going down a full clothing size.

Tolerability

across 163 dialogues with results

58%

Explicitly reported feeling well

33%

Mentioned at least one symptom

1–4 days

Side effect duration (n=16)

Percentages are of the 163 dialogues with results: 58% explicitly reported feeling well, 33% mentioned at least one adverse symptom, and the remaining ~9% did not give a clear wellbeing assessment. Side effects were mostly mild nausea, less often stomach heaviness and fatigue. Only 16 clients specified duration — all reported 1–4 days after the injection, after which symptoms resolved; there is no case lasting over a week in the conversations. The manager tracked wellbeing weekly.

Result as % of starting weight

n=33 · starting weight known

−5,1%

Median of body weight

−8,1%

Mean of body weight

33%

lost ≥10% of body weight

For 33 clients whose starting weight is known from the conversation, the median result is 5.1% of body weight (mean 8.1%, range 1.1–31.2%). A percentage is more meaningful than absolute kilograms: −5 kg for a 65 kg vs a 140 kg person are very different results. Figures are self-reported and interim: for many clients the program is still ongoing.

Weight loss pace

109 cases where the observation period is known from the conversation. The picture matches clinical GLP-1 program data: a fast start in the first month (−4…−6 kg), then a steady pace of 1–2 kg per month.

Observation period	Cases	Average loss	Median
~1 month	45	−5.8 kg	−4.0 kg
1.5–3 months	31	−6.2 kg	−5.0 kg
3–6 months	20	−8.2 kg	−4.0 kg

The “−4.8 kg first month” figure is the median for results reported at weeks 3–6 only (n=38). The “~1 month” row in the table uses a broader group of roughly monthly observations (n=45), so the samples and medians differ. Results are cumulative as of the client’s latest report, not final. Cases with a 6+ month period (n=13) are not included in the table: most are interim reports after breaks in the program and understate the real picture.

Our data vs a clinical trial

For context, we compare the nature of DOZA data with the randomized SURMOUNT-1 trial (tirzepatide). These are different data types — they are not directly comparable.

	SURMOUNT-1 (clinical trial)	DOZA report (real-world)
Data type	Randomized controlled trial (RCT)	Self-reported client data
Participants	N = 2,539	N = 163
Duration	72 weeks, fixed	Real-world, varying (3 weeks — 12 months)
Measurements	Standardized, in-clinic	As stated by clients, unverified
Outcome	Up to −20.9% of body weight (tirzepatide 15 mg)	Median −5.1% of body weight (n=33, interim)

These are different data types — they are not directly comparable. An RCT measures drug efficacy under controlled conditions over a fixed period; our report shows real interim results of support-program clients. SURMOUNT-1 source: Jastreboff et al., NEJM 2022.

Which products achieved the results

Mounjaro

141

Ozempic

Retatrutide

Biopatid

Other

Number of cases mentioning a product in the dialogue. Some clients combined or switched between products, so the sum exceeds 163. The total −1,026 kg reflects DOZA support-program clients overall, not the efficacy of any single product. Source: DOZA Telegram dialogues, August 2025 – July 2026.

What clients say

Verbatim quotes from conversations, anonymized. Messages marked "not for publication" were excluded.

«Amazing — already −18 kg! Nothing bothers me at all»
#1September 2025 · Mounjaro

«In 4 months I have already lost 16 kg — it is so cool, I am very happy»
#2May 2026 · Mounjaro

«−10 kg (was 76, now 66), already one clothing size down. Waist −6 cm, lower belly −9 cm. Feeling great too»
#3March 2026 · Mounjaro

«A year on injections now. Lost 15 kg. For me it is a great result, very happy»
#4June 2026 · Mounjaro

«Lost 15 kg: 7 kg in the first month, then 2–3 kg per month»
#5Mounjaro + Biopatid

«9 kg gone overall, I am very happy. Repeated my labs — HOMA index is normal»
#6March 2026 · Mounjaro + MOTS-c

Methodology

The full DOZA support conversation archive was analyzed: 1,272 dialogues, 67,918 text messages between 22.08.2025 and 15.07.2026. Of these, 908 dialogues were clients with confirmed orders. Client messages stating a numeric result ("lost N kg", "minus N", "from X to Y kg", cm measurements) were extracted automatically. Excluded: goal statements, results achieved before joining DOZA, questions, and messages about third parties. A client’s result is defined as the maximum weight loss they confirmed as of their latest report. Duplicates were removed. All data was anonymized: names, usernames and contacts were not used.

Methodology version: v1.018% of clients (163 of 908) provided an exact numeric result — the rest reported qualitatively or sent photos/voice messages

Download anonymized dataset (CSV)

163 rows with no personal data: report month, weight loss, starting weight (where known), % of body weight, observation period, products. License: CC BY-NC-ND 4.0.

Inclusion criteria

✓Client with a confirmed DOZA order
✓Numeric result reported by the client (kg or cm)
✓Result achieved during the DOZA program

Exclusion criteria

−Goal statements ("I want to lose N kg")
−Results achieved before joining DOZA
−Messages about third parties
−Duplicates and forwarded messages

Study limitations

!Self-reported data — as stated by clients, without medical verification of scales
!Sample — only clients who reported a numeric result (18%)
!This is not a clinical trial — a retrospective conversation analysis
!Results are individual and not guaranteed

Reviewed by

Анастасія Шаповал

Лікар, к.м.н. — спеціаліст з метаболічних програм

About this report

Who is accountable for each stage of the report, its version and the data cut-off date.

Data analysis

DOZA data team

conversation parsing, deduplication, statistics aggregation

Medical review

Anastasiia Shapoval

DOZA founder, metabolic-programs specialist

Methodology review

DOZA editorial team

inclusion/exclusion criteria, report versioning

Conflict of interest

All authors are affiliated with DOZA

the report reflects the company’s internal data

Report version

v1.0

Data cut-off

15.07.2026, 12:00 EEST

Next update

October 2026

Frequently asked questions

Based on 38 DOZA clients who reported results at weeks 3–6 of the program, the median is 4.8 kg in the first month (mean 6.2 kg). The pace then stabilizes at 1–2 kg per month — normal dynamics for GLP-1 programs.

DOZA Specialist

Every message included in the analysis contained a confirmed weight loss — from 0.5 to 26 kg, one in four over 10 kg. But the sample is drawn specifically from messages with a numeric result: clients without progress report numbers less often, so this does NOT mean 100% of all DOZA clients achieved a result. The pace is individual: it depends on starting weight, dose, nutrition and activity.