Key takeaway
Мунджаро (тирзепатід) і Оземпік (семаглутід) — два провідні GLP-1 продукти для корекції ваги. Мунджаро — подвійний агоніст GLP-1+GIP, демонструє -22.5% ваги за SURMOUNT-1. Оземпік — агоніст GLP-1, -14.9% за STEP-1. Обидва застосовуються 1 раз на тиждень підшкірно.
Which is better: Mounjaro or Ozempic?
Detailed comparison by efficacy (-22.5% vs -15%), price in Ukraine, and mechanism of action — DOZA specialist''s answer.
Full Comparison Table
| Parameter | Mounjaro | Ozempic |
|---|---|---|
| Active ingredient | Tirzepatide | Semaglutide |
| Manufacturer | Eli Lilly (USA) | Novo Nordisk (Denmark) |
| Mechanism of action | ✅ GLP-1 + GIP (dual) | GLP-1 only |
| Average weight loss | ✅ -22.5% (SURMOUNT-1) | -14.9% (STEP-1)* |
| Clinical trial | SURMOUNT-1 (2,539 participants) | STEP-1 (1,961 participants) |
| FDA approval year | 2022 | 2017 |
| Administration frequency | Once weekly | Once weekly |
| Administration method | Subcutaneous (KwikPen) | Subcutaneous (FlexTouch) |
| Dosing | ✅ 2.5, 5, 7.5, 10, 12.5, 15 mg | 0.25, 0.5, 1, 2 mg |
| Tolerability | ✅ Discomfort in 5-10% | Discomfort in 10-15% |
* STEP-1: semaglutide 2.4 mg/week (weight loss program dose, brand Wegovy). Ozempic is a T2D brand, max dose 2 mg.
The two pens are dialed differently: a full Mounjaro KwikPen stroke is 60 clicks (= pen strength), while Ozempic FlexTouch uses a different mechanism. To convert your prescribed Mounjaro dose into clicks, use the Mounjaro KwikPen clicks calculator.
Key Differences
Dual mechanism
Mounjaro acts on both GLP-1 and GIP receptors simultaneously. The dual mechanism provides 50% greater efficacy.
Clinical results
SURMOUNT-1: -22.5% body weight over 72 weeks. STEP-1: -15% over 68 weeks. Difference — 7.5 percentage points.
Tolerability
Mounjaro — discomfort in 5-10%, Ozempic — in 10-15%. Both have mild and temporary symptoms.
🏆 Verdict: Which to Choose?
Choose Mounjaro if:
- ✓ You want maximum results (-22.5% body weight)
- ✓ Diets and other approaches haven''t worked
- ✓ Ready to invest in the most effective product
- ✓ Better tolerability matters
Choose Ozempic if:
- ✓ Budget is limited (from 5,500 ₴/mo)
- ✓ Need to lose 10-15% body weight
- ✓ First experience with GLP-1 products
Not sure? A specialist will help you choose
💬 Free ConsultationGet your personalized program
Free. No obligations. A specialist will contact you within 5 minutes.
📚 Sources
- • SURMOUNT-1 (NEJM, 2022) — Tirzepatide for weight management, 2,539 participants, 72 weeks
- • STEP-1 (NEJM, 2021) — Semaglutide for weight management, 1,961 participants, 68 weeks
- • SURPASS-2 (NEJM, 2021) — Tirzepatide vs Semaglutide, head-to-head comparison
- • FDA Approval: Mounjaro (2022), Ozempic (2017)
Ozempic — What You Need to Know
Ozempic is a semaglutide-based product by Novo Nordisk, approved by the FDA in 2017.
The key difference from Mounjaro is the mechanism of action. Ozempic works only through GLP-1, while Mounjaro activates two receptors.
In Ukraine, Ozempic is harder to find due to supply issues. Meanwhile, you can order Mounjaro (all KwikPen doses) from DOZA.
Mounjaro or Ozempic — Which to Choose for Weight Loss
Key factors are efficacy, availability, and support. Mounjaro achieves -22.5% weight loss (SURMOUNT-1), Ozempic — -15%.
The DOZA Program includes product selection, 24/7 support, and monitoring. Learn more about weight loss.
How to Switch from Ozempic to Mounjaro
Switching is a common practice when hitting a plateau. Mounjaro''s dual mechanism often breaks through plateaus.
Transition protocol: last Ozempic injection → 7-day pause → Mounjaro 2.5 mg. Increase every 4 weeks.
A DOZA specialist guides the transition. Detailed comparison →
FAQ: Ozempic and Mounjaro
Mounjaro is more effective: -22.5% vs -15%. It acts on two receptors (GLP-1 + GIP).
Anastasia Shapoval
Metabolic Programs and Weight Control Specialist
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See Also
Mounjaro Program
What it is, how it works, who it''s for
Mounjaro Catalog
All KwikPen doses — from 8,000 ₴
Ozempic Catalog
Semaglutide catalog — pens and doses
Ozempic Price in Ukraine
Ozempic cost 2026
Ozempic — Overview
Semaglutide by Novo Nordisk
Mounjaro Reviews
Real results — before/after photos
Mounjaro Price
Program costs
Biopatid — Overview
Tirzepatide for weight loss
Retatrutide — Triple Agonist
Next-gen GLP-1/GIP/glucagon