TB-500

Standard manufacturer protocol: 20–40 clicks (500–1000 mcg) subcutaneously 3 times per week (1 click = 25 mcg). Set pen programmer to "20" (starting dose) or "40" (intensive recovery).

Subcutaneous injection in abdomen or front thigh — preferably closer to injury or inflammation site. After injection wait 10 seconds before withdrawing needle. Rotate injection sites.

1 pen 5 mg (200 clicks) — for ~3 weeks at standard dosing. Full course 30–45 days = 2 pens. For acute injury — continuation up to 6–8 weeks. Break between courses 4–6 weeks.

Classic synergy with BPC-157 — Pen Peptide offers ready blend BPC-157 + TB-500 (5+5 mg).

Storage: 2–8°C in refrigerator. MSSPT technology makes formula tolerant to short-term temperature deviations above 8°C during delivery.

Before starting — consultation with DOZA specialist to select regimen for your injury.

TB-500 (Thymosin Beta-4, Thymosin β4) is a small peptide of 43 amino acids that is naturally synthesized in the human body. Best known for its powerful ability to accelerate tissue regeneration: muscles, tendons, ligaments, cartilage, skin, and even nervous tissue. Actively studied in sports and rehabilitation medicine as one of the most potent recovery peptides.

In studies, TB-500 has shown potential in accelerating muscle and ligament recovery (30%+), stimulating new blood vessel growth (angiogenesis), cartilage and joint regeneration, improving microcirculation and heart health, accelerating skin and wound healing, stimulating hair growth, anti-inflammatory action, and reducing pain in injured areas. Research continues on its potential in spinal cord injuries, chronic joint diseases, and neurodegenerative conditions.

DOZA supplies TB-500 in pre-mixed pen format manufactured by Pen Peptide: 5 mg (200 clicks, 1 click = 25 mcg) in stabilized MSSPT form (Molecular Structure Stabilization Process Technology). Purity ≥98%, synthesis in certified GMP laboratories, storage 2–8°C with cold chain to your door. Classically combined with BPC-157 for synergistic recovery (available as separate pen or BPC-157 + TB-500 blend from Pen Peptide).

TB-500 is a synthetic fragment of Thymosin Beta-4, a natural 43-amino acid peptide with highest concentration in platelets (Goldstein et al.). Three key mechanisms: 1) actin sequestration — binds G-actin, allowing migration of progenitor cells to injury site for regeneration; 2) angiogenesis — stimulates formation of new capillaries in damaged tissue (Malinda et al., J Invest Dermatol 1999); 3) anti-fibrotic action — reduces scar tissue formation. Systemic action: no local injections near injury required. Standard stack with BPC-157: BPC works locally (tendons/GI) + TB-500 systemically (muscles/angiogenesis) — complementary pair.