How Many Kilograms You Lose on Mounjaro: Real Numbers for 1, 3, 6, and 12 Months
Weight Management and Healthy Lifestyle Experts

The question everyone asks before starting a weight loss program: exactly how many kilograms will I be able to lose? And most importantly — in what timeframe?
If you're looking for an honest answer without marketing promises, you're in the right place. We've gathered data from SURMOUNT-1, SURMOUNT-2, and SURMOUNT-5 clinical trials, where thousands of participants took Mounjaro under strict scientific supervision. Here's what they showed.
Quick answer for those in a hurry
On Mounjaro tirzepatide 15 mg, average weight loss is 20.9% over 72 weeks [2]. This means: if your starting weight is 100 kg, you can expect minus 21 kg in approximately 18 months.
But results depend on dose. On 5 mg participants lost about 15% weight, on 10 mg — 19.5% [2]. The placebo group showed only 3.1%.
What clinical studies say — concrete numbers
The SURMOUNT-1 study became the main source of data on tirzepatide effectiveness. It included adults with obesity or overweight without diabetes.
Here are the results over 72 weeks [2]:
Втрата ваги залежно від дози Мунджаро (Mounjaro)
| Доза | Втрата ваги | При вазі 80 кг | При вазі 100 кг | При вазі 120 кг |
|---|---|---|---|---|
| 5 мг | 15% | -12 кг | -15 кг | -18 кг |
| 10 мг | 19.5% | -15.6 кг | -19.5 кг | -23.4 кг |
| 15 мг | 20.9% | -16.7 кг | -20.9 кг | -25.1 кг |
| Плацебо | 3.1% | -2.5 кг | -3.1 кг | -3.7 кг |
What if you have diabetes? The SURMOUNT-2 study showed somewhat different results. In people with type 2 diabetes, the maximum 15 mg dose provided average weight loss of 15.7% [1]. This is less than SURMOUNT-1, but still a significant result.
You can find detailed information about all six doses in the article Mounjaro Dosage: Complete Table of 6 Doses.

What determines your personal result
Even in clinical studies, not all participants showed the same results. Here's what affects the final numbers.
1. Dose
Higher doses give better results. On 5 mg — 85% of participants lost at least 5% weight, on 15 mg — already 91% [2].
2. Starting weight and BMI
People with higher BMI usually lose more kilograms in absolute numbers. Although the percentage may be similar.
3. Adherence to regimen
Injection once a week, on the same day. Missed doses reduce effectiveness.
4. Physical activity
Studies recorded results without mandatory workouts. But moderate activity enhances the effect.
5. Nutrition
Mounjaro reduces appetite, but food quality also matters. Balanced nutrition helps preserve muscle mass.
У дослідженні SURMOUNT-5 на тирзепатиді 48.4% учасників досягли втрати понад 20%, а 31.6% — понад 25%. Водночас частина учасників показала менший результат. Ваш результат може бути як вищим, так і нижчим за середнє.
How to take the first step
Now you know the real numbers. Not advertising promises, but data from studies involving thousands of people.
Average loss on Mounjaro 15 mg: about 21% weight over 72 weeks. First results — already after 3-4 weeks. With 100 kg weight, this is approximately 21 kg.
Results depend on dose, program adherence, starting weight, and individual body characteristics. Not everyone achieves the average indicator, but over 90% of study participants lost at least 5% weight [2].
If you want to calculate a personalized forecast and choose the optimal program, DOZA specialists are ready to help. Consultation is free, and a test dose is available in the catalog.
Спеціаліст відповість протягом 15 хвилин
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Where to buy
DOZA supplies the products mentioned in this article with an official cold chain and 24/7 specialist support:
- Buy Mounjaro in Ukraine — DOZA catalog with all 6 doses (2.5–15 mg) and official 24h cold-chain delivery. Current Mounjaro prices.
📚 Sources & references
- 1Lilly's SURMOUNT-2 results published in The Lancet
Дані про втрату ваги 15.7% у людей з діабетом 2 типу на дозі 15 мг
- 2Understanding Your Tirzepatide Dosage for Weight Loss
Результати SURMOUNT-1: 20.9% втрати ваги на 15 мг, 19.5% на 10 мг, 15% на 5 мг за 72 тижні
- 3Early Dose Escalation of Tirzepatide after Switching from Semaglutide
Наукове порівняння ефективності тирзепатиду та семаглутиду при переході між продуктами
- 4Tirzepatide Dosing for Weight Loss in Units
Дані SURMOUNT-5: пряме порівняння 20.2% vs 13.7% та 50.3 vs 33.1 фунтів
- 5Zepbound (Tirzepatide) Dosage Guide
Схема титрування: старт з 2.5 мг, підвищення на 2.5 мг кожні 4 тижні
- 6Zepbound (Tirzepatide) Dosage Guide for Weight Loss - GoodRx
The typical starting Zepbound (tirzepatide) dosage for weight loss is 2.5 mg once a week for 4 weeks
❓ FAQ
In the first month on the starting dose of 2.5 mg, expect minus 2-3 kg. This is the adaptation period. More active weight loss begins from the second month on higher doses, when loss can be 3-5 kg monthly.
Anastasia Shapoval
Metabolic Programs and Weight Control Specialist
Article author
DOZA TeamWeight Management and Healthy Lifestyle Experts
The DOZA team of specialists with years of experience in personalized weight loss programs with Mounjaro. Every article is reviewed by experts and based on current scientific research.
About DOZA
DOZA is Ukraine's leading online medical weight-loss support service based on tirzepatide (Mounjaro) and GLP-1. Operating since 2023, 2,147+ clients, 24/7 specialist support, cold chain delivery across Ukraine.
The materials in this article are for informational purposes only. Please consult a specialist before starting any weight management program. For a free consultation message us on Telegram.
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